Tirzepatide may reduce the effectiveness of oral contraceptives, particularly during dose initiation and escalation
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11 12 GLP-1s lower blood sugar, blood pressure, body weight, and inflammationall of which reduce strain on the heart and blood vessels 13 GLP-1 receptors are found in the heart and arteries, where they may also improve endothelial function, increase nitric oxide, and reduce oxidative stress, helping stabilize plaque and improve how the heart uses energy, especially during stress
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Administered subcutaneously as an injection under the skin, it should be used in conjunction with a reduced-calorie diet and increased physical activity
