doi: 10.1136/gutjnl-2016-312729, 54
In hepatocellular carcinoma, glutathione S-transferase Pi (GSTP) translocates to the nucleus and modulates redox signaling via the Nrf2-Keap1 complex
It neutralizes free radicals, protects skin from environmental damage, and supports the skin's natural detoxification process
Diyabet, otoimmn hastalklar, nrodejeneratif hastalklar (Parkinson, Alzheimer), kalp hastalklar ve kronik inflamatuar durumlar gibi glutatyon seviyelerinin dk olduu bilinen hastalklarda, hekim kontrolnde destekleyici olarak kullanlabilir
Access this article Similar content being viewed by others Abbreviations -GCL: -glutamate cysteine ligase GGT: -glutamyl transferase BSO: L-buthionine-(S, R)-sulfoximine GPx: glutathione peroxidase GSH and GSSG: reduced and oxidized glutathione, respectively MAPK: mitogen-activated protein kinase miR: microRNA Nrf2: NF-E2-related factor 2 ROS: reactive oxygen species REFERENCES Scir, A., Cianfruglia, L., Minnelli, C., Bartolini, D., Torquato, P., Principato, G., Galli, F., and Armeni, T
By activating several proteins involved in the TSS pathway and cystine uptake, including CBS, SLC7A11, GCLC, and GCLM, DMF increased GSH levels and produced a ferroptosis scavenging effect
,aspect=ignore)
