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310 , R885R895 (2016)

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However, high levels can cause leptin resistance in the brain, leading to increased appetite and obesity

doi: 10.1007/s00406-009-0061-x 26 JerniganPLHoehnRSGrassmHEdwardsMJMllerCPKornhuberJet al

The list of experimental drugs is described in Table 1

Therefore, the changes in the dosage form or the combination with other drugs can further compensate for the weakness of low bioavailability of berberine