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Heroin withdrawal model, Exendin-4 intervention, and behavioral testing Forty-eight male C57BL/6J mice were randomly divided into a heroin-dependent group (n = 24) and a saline control group (n = 24)

Indole downregulates the expression of LBP in macrophages by activating HTR2B receptors and blocks the IB-/NF-B inflammatory signaling pathway, thus inhibiting the release of proinflammatory factors

DOI: Lee, M

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These findings provide a genomic framework for understanding the resistance potential of strain MVAST 0096