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The increasing prevalence of type 2 diabetes has resulted in larger numbers of patients with DGp

A 2012 analysis published in The Lancet estimated that beta-cell function is already reduced by roughly 50% by the time fasting glucose crosses the 100 mg/dL threshold [1]

The most common side effects include nausea, vomiting and constipation

Retatrutide is part of a new class of obesity medications sometimes nicknamed triple agonists. While popular drugs like Ozempic target one hormone pathway, GLP-1, and Zepbound activates two GLP-1 and GIP retatrutide targets three hormone receptors at once: GLP-1, GIP, and glucagon

Besides its glucose-lowering effect, GLP-1 has other extra-pancreatic effects

When looking at safety, most of the treatment-emergent adverse events (TEAEs) were mild to moderate in severity and gastrointestinal-related, according to the company