Kinnari PJ, Hyvnen ML, Mkil EM, Kaasalainen MH, Rivinoja A, Salonen JJ, et al
Best studied is the most this evidence base supports, and that is different from best or effective. Are these as good as minoxidil or finasteride
Documentation omits start and stop times
Starting with very low doses and monitoring response carefully is essential for this population
Incorporating checkpoint inhibitors that are specifically activated in the presence of inflammatory signals or within the tumor niche could further enhance specificity
It has been shown that perilesional melanocytes have a lower ratio of Bcl-2/Bax than control melanocytes, suggesting that melanocytes from patients with vitiligo are more susceptible to apoptosis activation due to altered Bcl-2 and Bax expression and that the balance between pro-apoptotic and anti-apoptotic proteins in vitiligo melanocytes is shifted towards apoptosis [44]