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The STEP and SUSTAIN trial data In the STEP and SUSTAIN trials, the incidence of thyroid cancer was not higher in the semaglutide group compared to the placebo group

It is a synthetic form of B12 with cyanide attached to the cobalamin (the B12)

Glutathione is the cornerstone of this protection

Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team

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