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Genetic and metabolic factors of individuals

Topiramate and phentermine are available combined into a single FDA-approved pill to treat obesity, called phentermine-topiramate ER

Serum superoxide dismutase (SOD) and glutathione (GSH) activities were also significantly increased in all NPs-treated groups compared with the control, indicating an upregulation of enzymatic and non-enzymatic antioxidant mechanisms

Simon et al., 1997)

Skin concerns: Dark circles (both pigmentation and vascular), fine lines and wrinkles around the eye, dehydration in this area, and puffiness

To diagnose Vitamin B12 deficiency, tests check serum levels and intrinsic factor antibodies