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In a follow-on study, general obese participants were administered either placebo or a dose-titrated regimen of MK-0493, in which participants received 400 mg PO QD of MK-0493 for seven days, with dose escalations of 200 mg every seven days until a final dose of 1000 mg PO QD was attained (48)

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EBioMedicine 95 , 104738 (2023)