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Conclusion In this review, we focused on glucagon/GLP-1 and associated drugs in the physiology of autophagy

Retatrutide and emerging GLP-1 medications Newer GLP-1 compounds like retatrutide follow the same subcutaneous injection principles

However, patients may notice changes in urination patterns indirectly related to improved blood glucose control, increased fluid intake to manage gastrointestinal symptoms, or concurrent medications

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The most common adverse effects from the SURMOUNT trials include: Nausea: 24-33% of participants (dose-dependent) Diarrhea: 18-25% of participants Constipation: 13-17% of participants Vomiting: 8-12% of participants Decreased appetite: 10-15% of participants Most of these effects are mild to moderate and occur primarily during dose escalation periods