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Hypomagnesemia recurred if PPI therapy was re-introduced[226] Another recent review of 4 cases examined the clinical consequences and mechanisms of electrolyte disorders that resulted from the elderly patients taking a PPI for a period of 1 to 13 years.[227] They developed severe low magnesium levels with low calcium levels, hypoparathyroidism (low parathyroid hormone), and extremely low urinary calcium and magnesium excretion

Potential complications can include: problems with the nervous system temporary infertility heart conditions pregnancy complications and congenital disabilities Adults with severe anaemia are also at risk of developing heart failure

Individuals with certain medical conditions or allergies should exercise caution

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It can be given via the NHS or privately