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The MHRA SmPC requires women on oral contraceptives to use additional barrier methods for 4 weeks after starting Mounjaro and after each dose increase due to reduced contraceptive exposure

Available from Accessed 18 August 2022 32

Real-world evidence like this is essential to understanding long-term patient outcomes

Participants received once-weekly subcutaneous injections of retatrutide at doses of 0.5 mg, 4 mg, 8 mg, or 12 mg, or placebo, over a 24-week treatment period, with gradual dose escalation to the target maintenance dose

488 Zimath, P