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doi: 10.1093/emboj/19.8.1777 43 ShahaniS.Braga-BasariaM.MaggioM.BasariaS

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In conclusion, we observed in vitro that, in APAP-induced hepatotoxicity, released HMGB1 from damaged hepatocytes contributed to the propagation of necrosis by a direct effect on neighboring hepatocytes in a feed-forward circuit