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62 A small study published in 2019 found exercise had a greater effect on cholesterol synthesis than calorie restriction

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The key strategies for minimizing regain during a short break include maintaining a high protein intake of 1.6-2.2 grams per kilogram of body weight daily, continuing or increasing resistance training to preserve muscle mass, planning meals in advance so hunger does not drive impulsive food choices, monitoring weight weekly but not daily to avoid overreacting to normal fluctuations, and staying hydrated since the body may retain more water without GLP-1 mediated effects on fluid balance

What is obesity

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Gipr fl/fl and Gipr Syn/ mice treated with mGIPR-Ab/P1 exhibited lower food intake (Fig