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Dr Wasserfall cautions that this is a lifelong treatment: Stopping the medication will result in the majority of the weight lost being regained. Studies have backed this up, showing that patients tend to regain most of the weight after discontinuing semaglutide or other GLP-1 receptor agonists

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The delayed gastric emptying is a core mechanism of how these medications work, but it does mean your digestive system needs more time to process food

J Plant Physiol 223:1931