On the one hand, this is really bad

GLP-1 and the Gut Microbiome: A Bidirectional Story The relevance of probiotics during GLP-1 use is grounded in real biology that goes beyond just "gut health." A 2026 narrative review in the British Journal of Clinical Pharmacology examined the bidirectional relationship between GLP-1 RAs and the gut microbiome.[4] The review documents that: GLP-1 RAs themselves modify gut microbial composition, with several studies showing shifts in the Firmicutes/Bacteroidetes ratio and increased abundance of certain Bifidobacterium and Lactobacillus species during treatment The gut microbiome in turn produces metabolites (short-chain fatty acids, secondary bile acids) that stimulate endogenous GLP-1 secretion Microbiome composition may influence inter-individual response to GLP-1 therapy through inflammation, insulin sensitivity, and metabolic pathways The implication for probiotic supplementation: the period during GLP-1 use is one of meaningful microbial change driven by altered transit, reduced food intake, and direct drug effects

Being older, female, or consuming insufficient protein were all linked to greater lean mass reduction during treatment
Natural ways to increase glutathione There are several ways you can boost your glutathione production naturally, which include: Eat more cruciferous vegetables: broccoli, brussel sprouts, cauliflower, kale, and watercress are all full to the brim with sulphur, which is used to produce glutathione in the human body
Bioengineering 11:492
"Shotsy tells you what you lost