The clinical protocol used in the SURMOUNT trials starts at 2.5 mg per week and increases in 2.5 mg increments, with 15 mg as the maximum weekly dose
De bijsluiter van Wegovy meldt ook haaruitval als veelvoorkomende bijwerking
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The final version will be published soon
This helps patients take the pressure off not feeling like they have to stop the medication quickly and can give them time to make new adjustments on their daily routine
To further expand the set of SpyLock-based bispecific formats for screening, it should also be possible to combine SpyLock with knob-in-hole Fc domains, with the caveat that exposed disulfides in the hinge region should either be avoided or, alternatively, reoxidized after bispecific generation 40