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Chronic sleep deprivation accelerates Sleep Glymphatic System Clears Brain Waste During Deep Sleep During deep sleep, the glymphatic system clears metabolic waste from the brain including beta-amyloid associated with Alzheimer's disease

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DNA damage can manifest in various forms, including specific modifications such as the oxidation of purine and pyrimidine bases, as well as more extensive structural alterations to the DNA molecule such as strand breaks or sister chromatid exchange