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10.1265/ehpm.2000.103 Environ Health Prev Med

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N.JinH.et al (2018)

Its Phase 2 obesity trial published in Lancet Diabetes & Endocrinology (2024) showed up to 18.7% weight loss at 46 weeks, while a separate Phase 2 MASH trial demonstrated significant MASH resolution, earning FDA Breakthrough Therapy Designation

Based on the findings, GLP-1RAs are evolving into multisystem therapies with expanding roles beyond diabetes, including cardiovascular, renal, and hepatic benefits, as well as potential neurocognitive benefits

190 TsuzukiN.MiyazawaT.MatsumotoK.NakamuraT.ShimaK

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