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The fact that the lean body mass decreased from four to eight weeks in the Setria and placebo groups suggests bad experimental design (the researchers hypothesized "eating less" and "over-reaching") -- these variables should be better accounted for in a proper study

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Say that two people both have a total B12 result of 300 One of them, in whom 20% is available to cells, may be fine

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doi: 10.1046/j.1471-4159.2003.01797.x