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His physical examination shows: BP: 170/95 mmHg - repeated and confirmed HR: 90 bpm and regular Fundi: Multiple retinal hemorrhages Chest: Few bibasilar crackles, (bubble bursting sound) Extremities: Mild edema to mid calf Feet: Decreased sensation to monofilament Capillary blood glucose (non-fasting): 250 mg/dL (normal ~120mg/dL) Question 2: Generate hypotheses about Mr

Clifton et al

At higher dosing levels than those used for diabetes, semaglutide produces significant appetite suppression and delayed gastric emptying, leading to sustained weight reduction

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