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It is known by various names: Silybum marianum Carduus Marianus Lady's Thistle Holy Thistle Marian Thistle The plant's characteristic white markings along the leaf veins are linked according to a medieval legend to a drop of the Virgin Mary's milk, which gave rise to the plant's name

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Furthermore, in intestinal intraepithelial lymphocytes, GLP-1R activation inhibits proximal T cell receptor signaling in a PKA-dependent manner, suppressing T cell activation and attenuating local IFN--driven inflammation (106)

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Tirzepatide sits in the Cardiometabolic Health bucket