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Notably, these studies mainly reported hepatic outcomes and cancer incidence rather than treatment-emergent adverse events, and detailed adverse effect data were not consistently available

It is not entirely clear how ALLO, which is a positive allosteric modulator of GABAergic neurotransmission, acts to improve memory function in this patient population, but it has been suggested that stress-induced changes in GABA receptor expression levels are likely to play a role in the etiology of depression

Influence of BMI-associated genetic variants and metabolic risk factors on weight loss with semaglutide: a longitudinal clinico-genomic cohort study

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doi: 10.1152/ajpheart.01015.2001 336 SenejaniA