Subsequent evaluations of the SUSTAIN and PIONEER trials have reaffirmed semaglutide's efficacy in diminishing both relative and absolute risks for significant adverse cardiovascular events in comparison to control therapies (Husain et al
doi: 10.1016/j.bcp.2020.114187 Summary Keywords GLP-1, GLP-1R, biased agonism, receptor trafficking, pancreatic beta cells Citation Marzook A, Tomas A and Jones B (2021) The Interplay of Glucagon-Like Peptide-1 Receptor Trafficking and Signalling in Pancreatic Beta Cells
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