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Key Takeaways Average weight loss for semaglutide and other GLP-1s How much weight should you lose on Mounjaro

Sip water throughout the day rather than consuming large volumes at once, which can contribute to gastric distension

Therefore, slower dose escalations could be used in older patients with comorbidities to help mitigate any AEs that might lead to treatment interruptions

And even now, being off the medication for almost a year, Im still having a lot of problems, Allen said in an interview with CNN

Since the medication slows digestion (gastric emptying), drinking enough water helps prevent constipation and supports overall metabolism

This is metabolic adaptation, and it's completely normal