This finding allows us to hypothesize that lipotoxicity induced in rat liver by sucrose feeding may be related to oxidative stress and to decreased GSH levels which are involved in insulin resistance
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Lixisenatide (Adylyxin) is an exendin-4 analogue with six Lys residues added at the C terminus to confer resistance to DPP-4 (22,282)
However, stacking two medications of the same class requires careful medical supervision, as additive effects on appetite, nausea, and gastric motility can occur
GLP-1 has a direct effect on adipose tissue
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