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The DISC activates caspase 8 (CASP8) or caspase 10 (CASP10) and downstream executioner caspase cascades

There are distinct hair loss symptom differences between men and women, as summarised below: Male pattern hair loss (androgenetic alopecia): Receding hairline, thinning at the temples, or hair loss at the crown, gradually leaving hair around the sides and back of the scalp Female pattern hair loss: General thinning across the scalp, most noticeable at the top or crown, with the frontal hairline usually preserved Rarer hair loss conditions There are some rarer hair loss conditions, and what a patient sees in their hair loss can vary from one condition to the next

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