semaglutide vs tirzepatide effectiveness comparison efficacy of versus in achieving therapeutic targets in type 2 diabetes: a post hoc analysis of the SURPASS-2 Trial Semaglutide vs Tirzepatide for Weight

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Some treatments like semaglutide may require ongoing use for continued results, while others like hormone therapy address underlying imbalances that, once corrected, may require less frequent intervention

But the results tend to be more durable because the underlying metabolic drivers have changed, not just suppressed

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Unlike older weight loss approaches, GLP-1 therapy addresses the hormonal mechanisms that drive hunger and calorie intake, making sustainable weight management more achievable