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Inflammation Modulation Unlike NSAIDs, which blunt inflammation indiscriminately, BPC-157 appears to reduce pro-inflammatory signalling while preserving the inflammatory response necessary for healing, a pattern summarized across the preclinical literature in a 2025 narrative review of BPC-157 for musculoskeletal healing McGuire et al

These are less effective than injections but still beneficial for certain conditions

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Individual variability in drug response : Genetic factors, baseline metabolic rate, and individual differences in GLP-1 and GIP receptor sensitivity contribute to variable responses