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HIV-1 Tat exposure induces a senescence-like phenotype in microglia with elevated senescence markers and pro-inflammatory cytokines [66, 67]
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The study of more than 3,127 adults found that it reduced weight by an average of 27.3 pounds (12.4%) among people who had obesity or overweight with at least one weight-related medical problem such as hypertension, who did not have diabetes, and who were using the highest dose of the medication, the company said in a news release
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