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Address the cellular foundation

For example, RSV enhances chemotherapeutic efficacy by promoting apoptosis and reducing drug resistance (86), while QUE amplifies methotrexates anti-inflammatory effects via dual targeting of oxidative stress and inflammation (45)

Additionally, studies have demonstrated that removing the insulin receptor in mice decreases blood glucose levels in response to IGF-1, indicating that IGF-1 can compensate for insulin's role in glucose metabolism to some extent (Clemmons, 2004)

Comput Intell Neurosci 2022:8568820