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The STAT News coverage noted that if the FDA ultimately reclassifies the compounds and they are produced by compounding pharmacies, clinicians would have discretion to prescribe them outside the narrow indications under review, meaning a substance reviewed only for ulcerative colitis could legally be prescribed for any purpose a physician deemed appropriate

It is strictly limited to serious, life-threatening conditions where all approved options are exhausted

L., Feng, Q., Li, S., Liang, S., Zhong, H., Liu, Z., Gao, Y., Zhao, H., Zhang, D., Su, Z., Fang, Z., Lan, Z., Li, J., Xiao, L., Li, J., Li, R., Li, X., Kristiansen, K

Research Background Isolated lipolytic activity Fragment 176-191 stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat formation) in adipose tissue models

Management of giant paraesophageal hernia

The related Athira compound fosgonimeton failed its Phase 2 Alzheimer's trial (LIFT-AD) in 2023 for efficacy, and Athira discontinued development