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Current evidence comes primarily from laboratory and preclinical studies

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, 44 , 771-786, doi: Schwarzer, R., Laurien, L., and Pasparakis, M

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The secretions of TNF and IL-6, the priming agents regulating the entry into G1 phase, were delayed leading to a postponed induction of the immediate-early genes such as c-Fos and Jun-B as well as a late and reduced activation of STAT3

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