glp-1 and kidneys the kidney: from physiology to pharmacology and outcomes in diabetes Discoveries in Medicine - GLP-1

As GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) become more widely used for weight loss and metabolic health, many individuals are discovering a lesser-known side effect: electrolyte imbalance

If you are prescribed oral semaglutide for type 2 diabetes, you may notice improvements in your blood sugar levels within just one or two weeks, especially when it comes to fasting glucose

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Disproportionality signals for IGE All five GLP-1RAs had statistically significant reporting odds ratios (RORs) for IGE: Semaglutide: ROR 24.8 Dulaglutide: ROR 14.7 Liraglutide: ROR 13.7 Exenatide: ROR 5.4 Tirzepatide: ROR 18.3 This analysis confirms that these drugs are significantly more likely to be reported in conjunction with IGE compared to other medications

Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans

Additionally, there have been rare reports of non-arteritic anterior ischaemic optic neuropathy (NAION) in observational studies of semaglutide, though a causal relationship has not been established and regulatory authorities continue to monitor this signal