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[Literature Review] Genetic architecture of the red blood cell proteome in genetically diverse mice reveals central role of hemoglobin beta cysteine redox status in maintaining circulating glutathione pools This paper investigates the genetic factors influencing red blood cell (RBC) resilience, focusing on how these factors affect RBCs during storage, which is crucial for transfusions

This convergence is empirically demonstrated by the concomitant reduction in the activation of caspase-3 and caspase-8, their essential adaptor FADD, and the downstream mediator GSDME

References: Adrian S, Scherzinger A, Sanyal A, Lake JE, Falutz J, Dub MP, Stanley T, Grinspoon S, Mamputu JC, Marsolais C, Brown TT, Erlandson KM

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