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Weight regain occurs rapidly after discontinuation, so many patients find long-term treatment continuation more sustainable than cycling on and off

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[DOI] [PubMed] [Google Scholar] 9.Skelton J.A., Irby M.B., Beech B.M., Rhodes S.D

1 The findings showed: Those not taking GLP-1 medications showed significantly more MS disease progression Higher risk of brainstem dysfunction (4.36% risk difference) Higher risk of cerebellar dysfunction (4.54% risk difference) Higher risk of bowel and bladder dysfunction (4.98% risk difference) As a retrospective analysis, this study has limitations including potential confounding factors, and definitive randomised controlled trials are needed to confirm any disease-modifying effects of GLP-1 medications in MS

Retrieved from Quddos, F., Hubshman, Z., Tegge, A., et al