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Metformin primarily reduces liver glucose production and improves insulin sensitivity, while GLP-1 agonists directly activate appetite-suppressing hormones in the brain

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It takes place over a long period of time, and can be potentially quicker than just diet and exercise alone

Peer review Peer review information Nature thanks Lee Henry and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Bacillus subtilis-derived peptides disrupt quorum sensing and biofilm assembly in multidrug-resistant Staphylococcus aureus