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This is clinically relevant, as IGF-I is generally less reliable of a biomarker for screening adults above 60 years with GHD and is a better screening and diagnostic biomarker in GHD in subjects with disease onset in childhood or early adulthood (86)

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Accessed March 17, 2026

8C), the VPA-ASD model was associated with an overgrowth of Clostridium and a near-absence of beneficial genera like Akkermansia and Lachnospiraceae_NK4A136_group