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The approaches work through different mechanisms and tissue concentrations

doi: 10.1300/J092v08n03_10 352 KennedyGNorrisGSpenceVMcLarenMBelchJJ

We suspect that performance benefit to be there

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Individuals with underlying diabetic gastroparesis, as well as other comorbidities such as obesity or gastroesophageal reflux disease, and symptoms of delayed gastric emptying (such as nausea, vomiting and abdominal pain) may be at higher risk of aspiration