Melanocortins are peptide hormones that are proteolytically cleaved from their precursor molecule known as pro-opiomelanocortin (POMC) and post-translationally modified into melanocyte-stimulating hormones (-, - and -MSH) and adrenocorticotrophic hormone (ACTH) (Nakanishi et al, 1979
By understanding the intricate interplay between OSMs and disease pathophysiology, can help enhance diagnostic precision, monitor disease progression, and tailor therapeutic interventions for individuals with IBD
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A 10% inoculum was used and the cultures were over-pressurised to 0.2 MPa with sterilised gas (80% H 2 and 20% CO 2 )