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2024 doi: 10.1177/15598276241280207

The timing of dose escalations should be individualized based on patient-specific factors including tolerance to the medications side effects, as determined by the prescribing provider

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171 IR is still the key link between diabetes and PD and may impair nigrostriatal dopamine function, 172 exacerbate nigrostriatal DA depletion, 173 and enhance cognitive impairment 174 and behavioral abnormalities