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Gp78 serves as an E3 ubiquitin ligase anchored to the endoplasmic reticulum (ER) membrane, participating in the ubiquitination and subsequent degradation of specific proteins, leading to mitophagy

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Circuit Court of Appeals heard arguments on whether the federal lawsuits should be revived

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37 Thus, outcomes relevant for seeking accelerated approval during future phase III RCTs with a longer duration of follow-up are ongoing

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