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T2DM patients quickly lose muscle mass and muscle function, especially in the lower body, which is essential for mobility balance due to all these reasons (138)

(Belardo et al., 2019

We observed decreased ROS-scavenging capacity with increased dimerization of the thiol groups in solution (formation of diNAC) in TBHP-induced ARPE-19 cells, providing insight on the balance between GSH/GSSG and the capacity for reduction of oxidative stress

Taken together, mHtt can impede the dynamic alterations of mitophagy, mitochondrial biogenesis, and mitochondrial fission/fusion, resulting in the disruption of mitochondrial structure and function

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10.1016/j.redox.2021.101979 107 Nascimento-CarvalhoB.da SilvaB