So far, with wegovy, patients gain back about half of the weight they lose
Ryan Breshears, chief behavioral health officer with Wellstar Health System
However, there were non-significant trends toward lower BMI (MD: -1.21, 95% CI [-2.66, 0.25], p= 0.10), body weight (MD: -3.00, 95% CI [-7.03, 1.04], p= 0.15), waist circumference (MD: -3.18, 95% CI [-7.77, 1.41], p= 0.17), diastolic blood pressure (MD: -4.07, 95% CI [-12.25, 4.12], p= 0.33), Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) (MD: -0.08, 95% CI [-1.10, 0.95], p= 0.89), AST (MD: -4.77, 95% CI [-10.74, 1.20], p= 0.12)., and ALT levels (MD: -4.28, 95% CI [-10.53, 1.97], p= 0.18) without reaching statistical significance
Semaglutide is the active ingredient in branded medications like Wegovy and Ozempic
doi: 10.1080/AC.70.1.3064591 24 ScaglioneRArganoCDi ChiaraTColombaDParrinelloGCorraoSet al
These results suggest that GLP-1R agonists are able to improve cognitive function by attenuating the oxidative stress and mitochondria dysfunction in CNS
