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Sitagliptin has been so successful because of the advantages in terms of efficacy and adverse effects on the one hand, and the successful development strategy of Merck on the other

In mammals, the key autophagy-regulating proteins, Bcl-2 and Beclin1, are localized to the endoplasmic reticulum and mitochondria [253]

Briefly, cells were cultured in media containing the indicated concentrations of MgSO4 under standard condition (25 mM glucose, 4 mM glutamine and 10% FBS) for 24 hours

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Free radical damage can slow these powerhouses down

Use of an integrated team approach provides the necessary comprehensive care