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Patients should be aware that hydroxocobalamin may cause side effects such as nausea, vomiting, and diarrhea

for example, isoniazid, cycloserine, penicillamine, and hydralazine each form complexes with B or otherwise interfere with B metabolism, potentially leading to deficiency and peripheral neuropathy

Published literature includes over 100 studies examining its effects in various in-vitro and animal model systems, with research groups investigating gastrointestinal cytoprotection, tendon and ligament tissue models, and neurological signaling pathways

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Athletes competing under anti-doping organizations should take this seriously