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However, achieving adequate enteral intake can be delayed or compromised in preterm infants, particularly those who are very immature or critically ill, heightening their vulnerability to carnitine insufficiency ( 4 The impact of supplementation of L-carnitine on preterm infants 4.1 Effect of L-carnitine supplementation on L-carnitine levels in preterm infants L-carnitine supplementation with parenteral nutrition can significantly increase the L-carnitine concentration in preterm infants (Figure 3)