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doi: 10.3389/fimmu.2017.01239 Received 27 June 2017 Accepted 19 September 2017 Published 29 September 2017 Volume 8 - 2017 Edited by Anna Rubartelli, IRCCS AOU San Martino IST, Italy Reviewed by Cecilia Garlanda, Istituto Clinico Humanitas, Italy
Intragastric and oral administration give detectable plasma levels for several hours in rodent studies, supported by the proline-rich sequence resisting cleavage by gastric proteases
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39.7% of patients achieved more than 25% weight loss compared to 0.3% on lifestyle changes alone
For these presentations, PRP and orthobiologic treatment have demonstrated meaningful clinical outcomes, with many patients returning to full activity without surgical intervention
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