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The metabolism of selenium has been reported to be affected by the microbiota thus playing part in regulating thyroid functions possibly via an increased expression of Pax8 and promoting its binding to the upstream enhancer region of the NIS, which is assumed to be due to enhanced selenium uptake to activate NIS promoter and hence induce NIS transcription (41)

[DOI] [PubMed] [Google Scholar] 235.Baird L., Yamamoto M

Pico-cell Plant Stem Cell Factor II

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