GLP-1s don't directly cause hair thinning, but the weight loss they bring on can trigger a temporary increase in shedding
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These include: Personal or family history of medullary thyroid carcinoma Personal history of Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Active or recent history of pancreatitis Pregnancy or planning to become pregnant Breastfeeding individuals Severe gastrointestinal disease or gastroparesis Patients with any of these conditions are advised against using GLP-1 medications, including compounded semaglutide, due to elevated risks identified in clinical studies
Many patients find that combining GLP-1 therapy with diet and exercise helps them lose weight more consistently than with lifestyle changes alone
A sweeping review of dozens of clinical trials suggests that todays most widely used GLP-1 receptor agonist drugs produce broadly consistent weight-loss results across age, race, ethnicity, and baseline health measures
BioMed research international, 2017, 6274854